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Human Alanine-Glyoxylate Aminotransferase 2 Lowers Asymmetric Dimethylarginine and Protects from Inhibition of Nitric Oxide Production

Elevated blood concentrations of asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric-oxide (NO) synthase, are found in association with diabetes, hypertension, congestive heart failure, and atherosclerosis. ADMA levels are controlled by dimethylarginine dimethylaminohydrolases (DDA...

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Detalhes bibliográficos
Main Authors: Rodionov, Roman N., Murry, Daryl J., Vaulman, Sarah F., Stevens, Jeff W., Lentz, Steven R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820767/
https://ncbi.nlm.nih.gov/pubmed/20018850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.091280
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