The attenuation of platelet and monocyte activation in a rabbit model of extracorporeal circulation by a nitric oxide releasing polymer

Nitric oxide (NO) has been shown to reduce thrombogenicity by decreasing platelet and monocyte activation by the surface glycoprotein, P-selectin and the integrin, CD11b, respectively. In order to prevent platelet and monocyte activation with exposure to an extracorporeal circulation (ECC), a nitric...

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Main Authors: Major, Terry C, Brant, David O, Reynolds, Melissa M, Bartlett, Robert H, Meyerhoff, Mark E, Handa, Hitesh, Annich, Gail M.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820718/
https://ncbi.nlm.nih.gov/pubmed/20042236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2009.12.028
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