IL-29 BINDS TO MELANOMA CELLS INDUCING JAK-STAT SIGNAL TRANSDUCTION AND APOPTOSIS

PURPOSE: Interlukin-29 (IL-29) is a member of the type III interferon (IFN) family that has been shown to have antiviral activity and inhibit cell growth. Melanoma cell lines were tested for the expression of the IL-29R and their response to IL-29. METHODS: Expression of IL-28R1 and IL-10R2, compone...

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Autori principali: Guenterberg, Kristan D., Grignol, Valerie P., Raig, Ene T., Zimmerer, Jason M., Chan, Anthony N., Blaskovits, Farriss M., Young, Gregory S., Nuovo, Gerard J., Mundy, Bethany L., Lesinski, Gregory B., Carson, William E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820597/
https://ncbi.nlm.nih.gov/pubmed/20103601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-09-0461
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