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The Göttingen minipig for assessment of retinoid efficacy in the skin: comparison of results from topically treated animals with results from organ-cultured skin

Göttingen minipigs were treated topically for 6 d with a novel retinoid (MDI 301) at concentrations ranging from 0.3% to 30% in cream vehicle. Treatment of the minipigs did not adversely affect their health (hematological and necropsy parameters) or produce changes in the skin suggestive of retinoid...

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Detalhes bibliográficos
Main Authors: Dame, Michael K., Paruchuri, Tejaswi, DaSilva, Marissa, Bhagavathula, Narasimharao, Ridder, William, Varani, James
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820557/
https://ncbi.nlm.nih.gov/pubmed/19536603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11626-009-9221-6
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