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Optimization of Adenoviral Vectors to Direct Highly Amplified Prostate-Specific Expression for Imaging and Gene Therapy

Gene expression-based imaging coupled to gene therapy will permit the prediction of therapeutic outcome. A significant challenge for successful gene therapy is to achieve a high-level of specific gene expression; however, tissue-specific promoters are weak. We postulate that if the weak activity of...

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Hlavní autoři: Sato, Makoto, Johnson, Mai, Zhang, Liqun, Zhang, Baohui, Le, Kim, Gambhir, Sanjiv S., Carey, Michael, Wu, Lily
Médium: Artigo
Jazyk:Inglês
Vydáno: 2003
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820502/
https://ncbi.nlm.nih.gov/pubmed/14599805
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