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Optimal assignment methods for ligand-based virtual screening

BACKGROUND: Ligand-based virtual screening experiments are an important task in the early drug discovery stage. An ambitious aim in each experiment is to disclose active structures based on new scaffolds. To perform these "scaffold-hoppings" for individual problems and targets, a plethora...

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Detalhes bibliográficos
Main Authors: Jahn, Andreas, Hinselmann, Georg, Fechner, Nikolas, Zell, Andreas
Formato: Artigo
Idioma:Inglês
Publicado em: Springer 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820492/
https://ncbi.nlm.nih.gov/pubmed/20150995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-2946-1-14
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