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Optimal assignment methods for ligand-based virtual screening

BACKGROUND: Ligand-based virtual screening experiments are an important task in the early drug discovery stage. An ambitious aim in each experiment is to disclose active structures based on new scaffolds. To perform these "scaffold-hoppings" for individual problems and targets, a plethora...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Jahn, Andreas, Hinselmann, Georg, Fechner, Nikolas, Zell, Andreas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820492/
https://ncbi.nlm.nih.gov/pubmed/20150995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1758-2946-1-14
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