Association of MMP - 12 polymorphisms with severe and very severe COPD: A case control study of MMPs - 1, 9 and 12 in a European population

BACKGROUND: Genetic factors play a role in chronic obstructive pulmonary disease (COPD) but are poorly understood. A number of candidate genes have been proposed on the basis of the pathogenesis of COPD. These include the matrix metalloproteinase (MMP) genes which play a role in tissue remodelling a...

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Detalhes bibliográficos
Main Authors: Haq, Imran, Chappell, Sally, Johnson, Simon R, Lotya, Juzer, Daly, Leslie, Morgan, Kevin, Guetta-Baranes, Tamar, Roca, Josep, Rabinovich, Roberto, Millar, Ann B, Donnelly, Seamas C, Keatings, Vera, MacNee, William, Stolk, Jan, Hiemstra, Pieter S, Miniati, Massimo, Monti, Simonetta, O'Connor, Clare M, Kalsheker, Noor
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820470/
https://ncbi.nlm.nih.gov/pubmed/20078883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2350-11-7
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