HIF-1α-Deficient Mice Have Increased Brain Injury after Neonatal Hypoxia-Ischemia

Evidence suggests that the activation of the transcription factor hypoxia-inducible factor 1α (HIF-1α) may promote cell survival in hypoxic or ischemic brain. To help understand the role of HIF-1α in neonatal hypoxic-ischemic brain injury, mice with conditional neuron-specific inactivation of HIF-1α...

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Détails bibliographiques
Auteurs principaux: Sheldon, R. Ann, Osredkar, Damjan, Lee, Christina L., Jiang, Xiangning, Mu, Dezhi, Ferriero, Donna M.
Format: Artigo
Langue:Inglês
Publié: S. Karger AG 2009
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Original Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820335/
https://ncbi.nlm.nih.gov/pubmed/19672073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000232563
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