Role of G Protein-Coupled Receptor Kinase-2 in Peroxisome Proliferator-Activated Receptor Gamma-Mediated Modulation of Blood Pressure and Renal Vascular Reactivity in SHR

BACKGROUND: Peroxisome proliferator-activated receptor γ (PPARγ), a nuclear transcription factor, modulates the expression/activity of G protein-coupled receptors (GPCRs), but its role in GPCR signaling is not clear. Increased GPCR kinase-2 (GRK-2) activity and receptor desensitization have been rep...

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Bibliografiske detaljer
Main Authors: Yousefipour, Zivar, Oyekan, Adebayo, Newaz, Mohammad
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2009
Fag:
Original Report: Laboratory Investigation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820323/
https://ncbi.nlm.nih.gov/pubmed/19420904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000218061
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