Isolation of the human anionic glutathione S-transferase cDNA and the relation of its gene expression to estrogen-receptor content in primary breast cancer.

The development of multidrug resistance in MCF7 human breast cancer cells is associated with overexpression of P-glycoprotein, changes in activities of several detoxication enzymes, and loss of hormone sensitivity and estrogen receptors (ERs). We have cloned the cDNA for one of the drug-detoxifying...

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Detalhes bibliográficos
Main Authors: Moscow, J A, Townsend, A J, Goldsmith, M E, Whang-Peng, J, Vickers, P J, Poisson, R, Legault-Poisson, S, Myers, C E, Cowan, K H
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC282004/
https://ncbi.nlm.nih.gov/pubmed/2842775
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