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Structures of the phosphorylated and VO(3)-bound 2H-phosphatase domain of Sts-2

The C-terminal domain of the suppressor of T cell receptor (TCR) signaling 1 and 2 (Sts-1 and -2) proteins has homology to the 2H-phosphatase family of enzymes. The phosphatase activity of the correspondent Sts-1 domain, Sts-1(PGM), is key for its ability to negatively regulate the signaling of memb...

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Autori principali: Chen, Yunting, Jakoncic, Jean, Parker, Kathlyn A., Carpino, Nick, Nassar, Nicolas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819845/
https://ncbi.nlm.nih.gov/pubmed/19627098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi9008648
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