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β2 integrins modulate the initiation and progression of atherosclerosis in low-density lipoprotein receptor knockout mice

AIMS: β2 integrin-mediated adhesion is thought to be a key event in cardiovascular disease. However, results of clinical trials targeting these molecules have been disappointing. Here, we investigated the effect of inactivation of β2 integrins at different stages of atherosclerosis by timed bone mar...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Merched, Aksam, Tollefson, Katherine, Chan, Lawrence
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819833/
https://ncbi.nlm.nih.gov/pubmed/19843511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvp347
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