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FLASH, a pro-apoptotic protein involved in activation of caspase-8 is essential for 3′ end processing of histone pre-mRNAs
3′ end processing of histone pre-mRNA requires U7 snRNP, which binds downstream of the cleavage site and recruits the endonuclease CPSF-73. U7 snRNP contains a unique Sm ring in which the canonical SmD2 protein is replaced by Lsm11. We used the yeast two-hybrid system to identify binding partners of...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819824/ https://ncbi.nlm.nih.gov/pubmed/19854135 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.08.016 |
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