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Gene inactivation of Na(+)/H(+) exchanger isoform 1 attenuates apoptosis and mitochondrial damage following transient focal cerebral ischemia

We investigated mechanisms underlying the Na(+)/H(+) exchanger isoform 1 (NHE1)-mediated neuronal damage in transient focal ischemia. Physiological parameters, body and tympanic temperatures, and regional cerebral blood flow during 30 min middle cerebral artery occlusion (MCAO) were similar in wild-...

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Detalhes bibliográficos
Main Authors: Wang, Yanping, Luo, Jing, Chen, Xinzhi, Chen, Hai, Cramer, Sam W., Sun, Dandan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819721/
https://ncbi.nlm.nih.gov/pubmed/18662334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2008.06304.x
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