Temporary Disruption of the Rat Blood-Brain Barrier with a Monoclonal Antibody: A Novel Method for Dynamic Manganese-Enhanced MRI

Manganese (Mn(2+)) has limited permeability through the blood-brain barrier (BBB). Opening the BBB such that a sufficient amount of Mn(2+) enters the extracellular space is a critical step for dynamic manganese-enhanced magnetic resonance imaging (ME-MRI) experiments. The traditional BBB opening met...

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Detalhes bibliográficos
Main Authors: Lu, Hanbing, Demny, Steven, Zuo, Yantao, Rea, William, Wang, Leiming, Chefer, Svetlana I., Vaupel, D. Bruce, Yang, Yihong, Stein, Elliot A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819608/
https://ncbi.nlm.nih.gov/pubmed/20026228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroimage.2009.12.053
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