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Sex Differences in μ-Opioid Receptor Expression in the Rat Midbrain Periaqueductal Gray Are Essential for Eliciting Sex Differences in Morphine Analgesia

Opioid-based narcotics are the most widely prescribed therapeutic agent for the alleviation of persistent pain; however, it is becoming increasingly clear that morphine is significantly less potent in women compared with men. Morphine primarily binds to μ-opioid receptors (MORs), and the periaqueduc...

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Autori principali: Loyd, Dayna R., Wang, Xioaya, Murphy, Anne Z.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819468/
https://ncbi.nlm.nih.gov/pubmed/19109484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4123-08.2008
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