Biosynthesis of a protein containing a nonprotein amino acid by Escherichia coli: L-2-aminohexanoic acid at position 21 in human epidermal growth factor.

Endeavoring to develop a method to biosynthesize proteins substituted with nonprotein amino acids, we attempted the incorporation of L-2-aminohexanoic acid (Ahx) into human epidermal growth factor (hEGF). Escherichia coli YK537 strain harboring plasmid pTA1522, which has the phoA promoter-phoA signa...

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Autors principals: Koide, H, Yokoyama, S, Kawai, G, Ha, J M, Oka, T, Kawai, S, Miyake, T, Fuwa, T, Miyazawa, T
Format: Artigo
Idioma:Inglês
Publicat: 1988
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC281944/
https://ncbi.nlm.nih.gov/pubmed/3045813
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