Luteolin triggers global changes in the microglial transcriptome leading to a unique anti-inflammatory and neuroprotective phenotype

BACKGROUND: Luteolin, a plant derived flavonoid, exerts a variety of pharmacological activities and anti-oxidant properties associated with its capacity to scavenge oxygen and nitrogen species. Luteolin also shows potent anti-inflammatory activities by inhibiting nuclear factor kappa B (NFkB) signal...

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Autors principals: Dirscherl, Konstantin, Karlstetter, Marcus, Ebert, Stefanie, Kraus, Dominik, Hlawatsch, Julia, Walczak, Yana, Moehle, Christoph, Fuchshofer, Rudolf, Langmann, Thomas
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2010
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819254/
https://ncbi.nlm.nih.gov/pubmed/20074346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-2094-7-3
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