Breast cancer cell lines contain functional cancer stem cells with metastatic capacity and a distinct molecular signature

Tumors may be initiated and maintained by a cellular subcomponent that displays stem cell properties. We have utilized the expression of aldehyde dehydrogenase as assessed by the ALDEFLUOR assay to isolate and characterize “cancer stem cell” populations in 33 cell lines derived from normal and malig...

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Autores principales: Charafe-Jauffret, Emmanuelle, Ginestier, Christophe, Iovino, Flora, Wicinski, Julien, Cervera, Nathalie, Finetti, Pascal, Hur, Min-Hee, Diebel, Mark E., Monville, Florence, Dutcher, Julie, Brown, Marthy, Viens, Patrice, Xerri, Luc, Bertucci, François, Stassi, Giorgio, Dontu, Gabriela, Birnbaum, Daniel, Wicha, Max S.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819227/
https://ncbi.nlm.nih.gov/pubmed/19190339
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2741
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