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Purification and Identification of Proteins That Bind to the Hereditary Persistence of Fetal Hemoglobin −198 Mutation in the γ-Globin Gene Promoter

Expression of the γ-globin gene is silenced in adult humans. However, certain point mutations in the γ-globin gene promoter are capable of maintaining expression of this gene during adult erythropoiesis, a condition called non-deletion hereditary persistence of fetal hemoglobin (HPFH). Among these,...

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Détails bibliographiques
Auteurs principaux: Olave, Ivan A., Doneanu, Catalin, Fang, Xiangdong, Stamatoyannopoulos, George, Li, Qiliang
Format: Artigo
Langue:Inglês
Publié: 2006
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819221/
https://ncbi.nlm.nih.gov/pubmed/17114178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M610404200
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