Caspase Mediated Cleavage, IAP Binding and Ubiquitination: Linking Three Mechanisms Crucial for Drosophila NF-κB Signaling

Innate immune responses are critical for the immediate protection against microbial infection. In Drosophila, infection leads to the rapid and robust production of antimicrobial peptides, through two NF-κB signaling pathways - IMD and Toll. The IMD pathway is triggered by DAP-type peptidoglycan, com...

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Bibliographische Detailangaben
Hauptverfasser: Paquette, Nicholas, Broemer, Meike, Aggarwal, Kamna, Chen, Li, Husson, Marie, Ertürk-Hasdemir, Deniz, Reichhart, Jean-Marc, Meier, Pascal, Silverman, Neal
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819219/
https://ncbi.nlm.nih.gov/pubmed/20122400
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.12.036
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