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Anemia lessens and its prevention with recombinant human erythropoietin worsens glomerular injury and hypertension in rats with reduced renal mass.

Chronic renal disease is frequently characterized by anemia, which may modify systemic and renal hemodynamics. In adult Munich-Wistar rats, the mild anemia (hematocrit, approximately equal to 42 vol/dl) that accompanies five-sixths nephrectomy was either made more severe (approximately equal to 30 v...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Garcia, D L, Anderson, S, Rennke, H G, Brenner, B M
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 1988
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281921/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3413082/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.6142
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