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Essential fatty acid deficiency prevents multiple low-dose streptozotocin-induced diabetes in CD-1 mice.

Multiple i.p. injections of low-dose streptozotocin (40 mg/kg) produce insulitis, beta cell destruction, and diabetes in male CD-1 mice. Recent data also suggest that macrophages figure in the low-dose streptozotocin model. Because other recent studies have shown that essential fatty acid deficiency...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Wright, J R, Lefkowith, J B, Schreiner, G, Lacy, P E
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 1988
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281920/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3045812/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.6137
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