Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro.

The sulfated polysaccharides dextran sulfate and heparin have proved to be potent and selective inhibitors of human immunodeficiency virus type 1 (HIV-1) in vitro. Dextran sulfate (Mr 5000) and heparin (Mr 15,000) completely protected MT-4 cells against HIV-1-induced cytopathogenicity at a concentra...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Baba, M, Pauwels, R, Balzarini, J, Arnout, J, Desmyter, J, De Clercq, E
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1988
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281919/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2457906/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.6132
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