Mechanism of inhibitory effect of dextran sulfate and heparin on replication of human immunodeficiency virus in vitro.

The sulfated polysaccharides dextran sulfate and heparin have proved to be potent and selective inhibitors of human immunodeficiency virus type 1 (HIV-1) in vitro. Dextran sulfate (Mr 5000) and heparin (Mr 15,000) completely protected MT-4 cells against HIV-1-induced cytopathogenicity at a concentra...

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Publicado en:	Proc Natl Acad Sci U S A
Principais autores:	Baba, M, Pauwels, R, Balzarini, J, Arnout, J, Desmyter, J, De Clercq, E
Formato:	Artigo
Idioma:	Inglês
Publicado:	National Academy of Sciences 1988
Assuntos:	Research Article
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281919/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2457906/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.6132
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