Expression of the human beta-globin gene following retroviral-mediated transfer into multipotential hematopoietic progenitors of mice.

Efficient transfer of the beta-globin gene into primitive hematopoietic progenitors was achieved with consistent and significant expression in the progeny of those cells. Retroviral vectors containing the intact genomic human beta-globin gene and the neomycin (G418)-resistance (neoR) gene were const...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Karlsson, S, Bodine, D M, Perry, L, Papayannopoulou, T, Nienhuis, A W
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281905/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3413076/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.6062
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