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Constitutive Overexpression of Pigment Epithelium–Derived Factor Inhibition of Ocular Melanoma Growth and Metastasis
PURPOSE. Pigment epithelium–derived factor (PEDF) is known to be an angiogenesis suppressor and to have antitumor effects. This study investigates whether constitutive overexpression of PEDF inhibits the growth and hepatic micrometastasis of ocular melanoma. METHODS. Real-time RT-PCR was used to det...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Association for Research in Vision and Ophthalmology, Inc.
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819011/ https://ncbi.nlm.nih.gov/pubmed/19661223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.09-4138 |
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