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Allelic sequence variation of the HLA-DQ loci: relationship to serology and to insulin-dependent diabetes susceptibility.

Analysis of sequence variation in the polymorphic second exon of the major histocompatibility complex genes HLA-DQ alpha and -DQ beta has revealed 8 allelic variants at the alpha locus and 13 variants at the beta locus. Correlation of sequence variation with serologic typing suggests that the DQw2,...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Horn, G T, Bugawan, T L, Long, C M, Erlich, H A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1988
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281895/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2842756/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.6012
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