Distinct defects in collagen microarchitecture underlie vessel-wall failure in advanced abdominal aneurysms and aneurysms in Marfan syndrome

An aneurysm of the aorta is a common pathology characterized by segmental weakening of the artery. Although it is generally accepted that the vessel-wall weakening is caused by an impaired collagen metabolism, a clear association has been demonstrated only for rare syndromes such as the vascular typ...

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Autori principali: Lindeman, Jan H. N., Ashcroft, Brian A., Beenakker, Jan-Willem M., van Es, Maarten, Koekkoek, Nico B. R., Prins, Frans A., Tielemans, Jarl F., Abdul-Hussien, Hazem, Bank, Ruud A., Oosterkamp, Tjerk H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2009
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818895/
https://ncbi.nlm.nih.gov/pubmed/20080766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0910312107
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