Cell contacts are required for induction by cortisol of glutamine synthetase gene transcription in the retina.
In embryonic neural retina the enzyme glutamine synthetase [GS; L-glutamate:ammonia ligase (ADP-forming), EC 6.3.1.2] is a glia-specific differentiation marker inducible with cortisol. We show that cortisol elicits GS mRNA accumulation by stimulating transcription of the GS gene and that this stimul...
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| Pubblicato in: | Proc Natl Acad Sci U S A |
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| Autori principali: | , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
1988
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281889/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2901094/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.5981 |
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