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Efficacy of ST-246 versus lethal poxvirus challenge in immunodeficient mice

The threat of smallpox as a bioweapon and the emerging threat of human monkeypox, among other poxviral diseases, highlight the need for effective poxvirus countermeasures. ST-246, which targets the F13L protein in vaccinia virus and its homologs in other orthopoxvirus species, provides full protecti...

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Detalhes bibliográficos
Main Authors: Grosenbach, Douglas W., Berhanu, Aklile, King, David S., Mosier, Stacie, Jones, Kevin F., Jordan, Robert A., Bolken, Tove’ C., Hruby, Dennis E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818887/
https://ncbi.nlm.nih.gov/pubmed/20080762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0912134107
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