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Assessing Efficacy in Early-phase Cancer Prevention Clinical Trials: The Case of Ki-67 in the Lung
This perspective on Kim et al. (beginning on p. XX in this issue of the journal) examines the value of the Ki-67 proliferation index as a surrogate endpoint in early-phase clinical lung-cancer prevention trials. The clinical trial of Kim et al. demonstrates an effect of the cyclooxygenase-2–selectiv...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818869/ https://ncbi.nlm.nih.gov/pubmed/20103726 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-09-0268 |
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