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Histone H3 Lysine 27 Methylation Asymmetry on Developmentally-Regulated Promoters Distinguish the First Two Lineages in Mouse Preimplantation Embryos

First lineage specification in the mammalian embryo leads to formation of the inner cell mass (ICM) and trophectoderm (TE), which respectively give rise to embryonic and extraembryonic tissues. We show here that this first differentiation event is accompanied by asymmetric distribution of trimethyla...

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Detalhes bibliográficos
Main Authors: Dahl, John Arne, Reiner, Andrew H., Klungland, Arne, Wakayama, Teruhiko, Collas, Philippe
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818844/
https://ncbi.nlm.nih.gov/pubmed/20161773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009150
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