Brain-selective over-expression of human Angiotensin Converting Enzyme 2 attenuates neurogenic hypertension

RATIONALE: Angiotensin converting enzyme 2 (ACE2) is a new member of the brain renin-angiotensin system, that might be activated by an overactive renin-angiotensin system. OBJECTIVE: To clarify the role of central ACE2 using a new transgenic mouse model with hACE2 under the control of a synapsin pro...

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Bibliographic Details
Main Authors: Feng, Yumei, Xia, Huijing, Cai, Yanhui, Halabi, Carmen M., Becker, Lenice K., Santos, Robson A.S., Speth, Robert C., Sigmund, Curt D., Lazartigues, Eric
Format: Artigo
Language:Inglês
Published: 2009
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818798/
https://ncbi.nlm.nih.gov/pubmed/19926873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.109.208645
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