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UV-induced association of the CSB remodeling protein with chromatin requires ATP-dependent relief of N-terminal autorepression

The ATP-dependent chromatin remodeler CSB is essential for transcription-coupled DNA repair, and mutations in CSB lead to Cockayne syndrome. Here we examined the recruitment of CSB to chromatin after UV irradiation and uncovered a regulatory mechanism that ensures the specific association of this re...

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Bibliografske podrobnosti
Main Authors: Lake, Robert J., Geyko, Anastasia, Hemashettar, Girish, Zhao, Yu, Fan, Hua-Ying
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818792/
https://ncbi.nlm.nih.gov/pubmed/20122405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.10.027
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