Epstein-Barr virus-encoded EBNA1 inhibits the canonical NF-κB pathway in carcinoma cells by inhibiting IKK phosphorylation

BACKGROUND: The Epstein-Barr virus (EBV)-encoded EBNA1 protein is expressed in all EBV-associated tumours, including undifferentiated nasopharyngeal carcinoma (NPC), where it is indispensable for viral replication, genome maintenance and viral gene expression. EBNA1's transcription factor-like...

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Detalhes bibliográficos
Main Authors: Valentine, Robert, Dawson, Christopher W, Hu, Chunfang, Shah, Khilan M, Owen, Thomas J, Date, Kathryn L, Maia, Sonia P, Shao, Jianyong, Arrand, John R, Young, Lawrence S, O'Neil, John D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818691/
https://ncbi.nlm.nih.gov/pubmed/20051109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-1
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