A degenerate HLA-DR epitope pool of HER-2/neu reveals a novel in vivo immunodominant epitope, HER-2/neu(88-102)

PURPOSE: Over the past two decades, there has been significant interest in targeting HER-2/neu in immune-based approaches for the treatment of HER-2/neu+ cancers. For example, peptide vaccination using a CD8 T cell activating HER-2/neu epitope (amino acids 369-377) is an approach that is being consi...

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Autori principali: Karyampudi, Lavakumar, Formicola, Courtney, Erskine, Courtney L., Maurer, Matthew J., Ingle, James N., Krco, Christopher J., Wettstein, Peter J., Kalli, Kimberly R., Fikes, John D., Beebe, Melanie, Hartmann, Lynn C., Disis, Mary L., Ferrone, Soldano, Ishioka, Glenn, Knutson, Keith L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818599/
https://ncbi.nlm.nih.gov/pubmed/20103660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2781
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