Antitumor activity of targeting Src kinases in endothelial and myeloid cell compartments of the tumor microenvironment

PURPOSE: Several Src family kinase (SFK) inhibitors have entered clinical trials based on their direct effects against tumor cells. Here we characterize the effects of targeting Src kinases on the tumor microenvironment and how these effects influence tumor growth. EXPERIMENTAL DESIGN: Human cancer...

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Hauptverfasser: Liang, Wei, Kujawski, Maciej, Wu, Jun, Lu, Jianming, Herrmann, Andreas, Loera, Sofia, Yen, Yun, Lee, Frank, Yu, Hua, Wen, Wei, Jove, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818562/
https://ncbi.nlm.nih.gov/pubmed/20103658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-1486
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