Specificity of action of guanine nucleotide-binding regulatory protein subunits on the cardiac muscarinic K+ channel.

The cardiac muscarinic receptor stimulates a potassium-selective ionic current (IK.ACh) through activation of a guanine nucleotide-binding regulatory protein. Purified alpha and beta gamma subunits of the guanine nucleotide-binding regulatory protein have each been reported to open the K+ channel. W...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Logothetis, D E, Kim, D H, Northup, J K, Neer, E J, Clapham, D E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281855/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2457901/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.16.5814
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