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A palindrome-mediated mechanism distinguishes translocations involving LCR-B of chromosome 22q11.2

Two known recurrent constitutional translocations, t(11;22) and t(17;22), as well as a non-recurrent t(4;22), display derivative chromosomes that have joined to a common site within the low copy repeat B (LCR-B) region of 22q11.2. This breakpoint is located between two AT-rich inverted repeats that...

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Autors principals: Gotter, Anthony L., Shaikh, Tamim H., Budarf, Marcia L., Rhodes, C. Harker, Emanuel, Beverly S.
Format: Artigo
Idioma:Inglês
Publicat: 2003
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818528/
https://ncbi.nlm.nih.gov/pubmed/14613967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddh004
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