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Palindromic AT-Rich Repeat in the NF1 Gene Is Hypervariable in Humans and Evolutionarily Conserved in Primates
Palindromic sequences are dispersed in the human genome and may cause chromosomal translocations in humans. They constitute unsequenced gaps in the human genome because of their resistance to PCR amplification, cloning into vectors, and sequencing. We have overcome these difficulties by using a comb...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2005
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818517/ https://ncbi.nlm.nih.gov/pubmed/16116616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.20228 |
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