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Monitoring of antigen-specific CD8 T cells in patients with type 1 diabetes treated with antiCD3 monoclonal antibodies

The way in which anti-CD3 monoclonal antibodies (mAbs) modify human immune responses in Type 1 diabetes (T1DM) is not known. We prepared a panel of Class I HLA-A2.1 tetramers with peptides from diabetes-associated antigens and studied the frequency and phenotype of the cells in patients with T1DM an...

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Hlavní autoři: Cernea, Simona, Herold, Kevan C
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818312/
https://ncbi.nlm.nih.gov/pubmed/19837003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clim.2009.09.005
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