The 6-nucleotide deletion variant in the CASP8 promoter region is inversely associated with risk of squamous cell carcinoma of the head and neck

Caspase 8 is an apoptosis-related cysteine peptidase involved in the death receptor pathway and likely in the mitochondrial pathway. A CASP8 promoter-region 6-nucleotide deletion/insertion (-652 6N ins/del) and a coding region D302H polymorphism are reportedly important in cancer development, but no...

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Detalhes bibliográficos
Main Authors: Li, Chunying, Lu, Jiachun, Liu, Zhensheng, Wang, Li-E, Zhao, Hui, El-Naggar, Adel K., Sturgis, Erich M., Wei, Qingyi
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818282/
https://ncbi.nlm.nih.gov/pubmed/20086182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-08-0228
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