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The rad52-Y66A allele alters the choice of donor template during spontaneous chromosomal recombination

Spontaneous mitotic recombination is a potential source of genetic changes such as loss of heterozygosity and chromosome translocations, which may lead to genetic disease. In this study we have used a rad52 hyper-recombination mutant, rad52-Y66A, to investigate the process of spontaneous heteroallel...

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Bibliographische Detailangaben
Hauptverfasser: de Mayolo, Adriana Antúnez, Sunjevaric, Ivana, Reid, Robert, Mortensen, Uffe H., Rothstein, Rodney, Lisby, Michael
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818265/
https://ncbi.nlm.nih.gov/pubmed/19892607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2009.10.001
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