Transforming growth factor beta inhibits formation of osteoclast-like cells in long-term human marrow cultures.

Transforming growth factor beta (TGF-beta), a polypeptide present in abundant amounts in bone matrix, was examined for its effects on osteoclast formation by using a human bone marrow culture system in which multinucleated cells (MNCs) with osteoclast characteristics form. TGF-beta strongly inhibite...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Chenu, C, Pfeilschifter, J, Mundy, G R, Roodman, G D
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1988
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281824/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3165196/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.15.5683
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