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Erythropoietin Receptor Signaling Regulates Both Erythropoiesis and Megakaryopoiesis In Vivo
Transgenic expression of a gain-of-function truncated mouse erythropoietin receptor gene (EpoR) leads to expansion of the HSC pool in response to human erythropoietin (Epo). We have re-examined this observation using a knock-in mouse model, wherein the mouse EpoR gene was replaced in its proper gene...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2818228/ https://ncbi.nlm.nih.gov/pubmed/19836979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2009.09.007 |
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