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Erythropoietin Receptor Signaling Regulates Both Erythropoiesis and Megakaryopoiesis In Vivo

Transgenic expression of a gain-of-function truncated mouse erythropoietin receptor gene (EpoR) leads to expansion of the HSC pool in response to human erythropoietin (Epo). We have re-examined this observation using a knock-in mouse model, wherein the mouse EpoR gene was replaced in its proper gene...

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Détails bibliographiques
Auteurs principaux: Huang, Xiaosong, Pierce, L. Jeanne, Chen, George L., Chang, Ko-Tung, Spangrude, Gerald J., Prchal, Josef T.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818228/
https://ncbi.nlm.nih.gov/pubmed/19836979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcmd.2009.09.007
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