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Molecular basis of human growth hormone gene deletions.

Crossover sites resulting from unequal recombination within the human growth hormone (GH) gene cluster that cause GH1 gene deletions and isolated GH deficiency type 1A were localized in nine patients. In eight unrelated subjects homozygous for 6.7-kilobase (kb) deletions, the breakpoints are within...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Vnencak-Jones, C L, Phillips, J A, Chen, E Y, Seeburg, P H
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 1988
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281810/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2840669/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.85.15.5615
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