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Variation In Genes Required For Normal Mitosis And Risk Of Breast Cancer

The down-regulation of genes involved in normal cell division can cause aberrant mitoses and increased cell death. Surviving cells exhibit aneuploidy and/or polyploidy. Since mitotic disruption has been linked with tumor development and progression, alterations in the expression or activity of these...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Olson, JE, Wang, X, Goode, EL, Pankratz, VS, Fredericksen, ZS, Vierkant, RA, Pharoah, P, Cerhan, JR, Couch, FJ
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818059/
https://ncbi.nlm.nih.gov/pubmed/19377877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10549-009-0386-1
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