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Imaging Myosin-X at the Single-Molecule Level Reveals a Novel Form of Motility in Filopodia

Although many proteins, receptors, and viruses are transported rearward along filopodia by retrograde actin flow[1-3], it is less clear how molecules move forward in filopodia. Myosin-X (Myo10) is an actin-based motor hypothesized to use its motor activity to move forward along actin filaments to th...

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Detalhes bibliográficos
Main Authors: Kerber, Michael L., Jacobs, Damon T., Campagnola, Luke, Dunn, Brian D., Yin, Taofei, Sousa, Aurea D., Quintero, Omar A., Cheney, Richard E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817954/
https://ncbi.nlm.nih.gov/pubmed/19398338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2009.03.067
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