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HOP is a monomer: Investigation of the oligomeric state of the co-chaperone HOP

The co-chaperone Hsp70-Hsp90 organizing protein (HOP) plays a central role in protein folding in vivo, binding to both Hsp70 and Hsp90 and bringing them together in a functional complex. Reports in the literature concerning the oligomeric state of HOP have been inconsistent—is it a monomer, dimer, o...

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Hlavní autoři: Yi, Fang, Doudevski, Ivo, Regan, Lynne
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley Subscription Services, Inc., A Wiley Company 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817835/
https://ncbi.nlm.nih.gov/pubmed/19866486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.278
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