ASPM-associated stem cell proliferation is involved in malignant progression of gliomas and constitutes an attractive therapeutic target

BACKGROUND: ASPM (Abnormal Spindle-like Microcephaly associated) over-expression was recently implicated in the development of malignant gliomas. RESULTS: To better characterize the involvement of ASPM in gliomas, we investigated the mRNA expression in 175 samples, including 8 WHO Grade II, 75 WHO G...

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Detalhes bibliográficos
Main Authors: Bikeye, Sandra-Nadia Ngwabyt, Colin, Carole, Marie, Yannick, Vampouille, Raphaël, Ravassard, Philippe, Rousseau, Audrey, Boisselier, Blandine, Idbaih, Ahmed, Calvo, Charles Félix, Leuraud, Pascal, Lassalle, Myriam, El Hallani, Soufiane, Delattre, Jean-Yves, Sanson, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Primary research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817685/
https://ncbi.nlm.nih.gov/pubmed/20142996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-10-1
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